Abstract

MEDIN CATOIRA, J.; MEDIN MEDIN, J.H.  and  LOPEZ BERRUEZO, J.. Ocular side effects with topiramate: A case discussion and review of the literature. Sanid. Mil. [online]. 2011, vol.67, n.2, pp.100-104. ISSN 1887-8571.

Clinical case: We describe a case of acute bilateral ocular myopia associate to ocular hypertension by angle-closure secondary oral treatment with topiramate. Review: We review the main ocular effects related to the treatment with topiramate, such as angle-closure glaucoma, hypertension, secondary myopia, or retinal toxicity. Symptoms typically occur in the first weeks of the topiramate therapy, or when the dose is duplicate. The disease and symtoms dissapear when the medication is discontinued. Conclusion: The topiramato is a drug used mainly as anti-epileptic, and also in other variable neurological disorders as migraines, alcoholism, spasms, neuralgias and obesity and bulimia, among others. The secondary ocular effects must be known by the ophtalmologist and communicated to the patient and his family at the beginning of the treatment.

Keywords : Topiramate; angle closure glaucoma; secondary myopia; retinal toxicity.

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