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Revista de Osteoporosis y Metabolismo Mineral
On-line version ISSN 2173-2345Print version ISSN 1889-836X
Abstract
LEON, S et al. 25-OH-vitamin D and reversal of metabolic comorbidities associated with obesity after bariatric surgery. Rev Osteoporos Metab Miner [online]. 2022, vol.14, n.1, pp.42-47. Epub Aug 22, 2022. ISSN 2173-2345. https://dx.doi.org/10.4321/s1889-836x2022000100005.
Introduction:
Obesity is a public health concern in which defects in the endocrine system occur, which may lead to metabolic diseases. Bariatric surgery (BS) has proved to be more effective in weight loss and reversal of comorbidities (especially inflammatory and metabolic). The underlying mechanisms related to the reversal of comorbidities are still poorly understood. Patients undergoing BS routinely receive vitamin D supplements, so its role in the reversal of comorbidities may be relevant.
Objectives:
To determine the relationship between 25-OH-vitamin D levels, the prevalence of metabolic comorbidities before BS and 6 months post-op.
Results:
328 patients were evaluated, who showed significant loss of weight and lean mass 6 months after BS. Serum levels of 25-OH-vitamin D increased in parallel with an increase in supplementation. However, no correlations were observed with the presence of baseline metabolic comorbidities or at 6 months of BS. Serum levels of 25-OH-vitamin D were correlated with some parameters of body composition independently of the reversal of comorbidities.
Conclusions:
Bariatric surgery was associated with a significant improvement in metabolic comorbidities in the patients studied independently of 25-OH-vitamin D serum levels.
Keywords : vitamin D; obesity; metabolic comorbidities; reversal.