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Enfermería Nefrológica

On-line version ISSN 2255-3517Print version ISSN 2254-2884

Abstract

GUERRERO-RODRIGUEZ, Elena et al. Reactogenicity and immunogenicity after inoculation of SARS-CoV-2 vaccine in dialysis care workers. Enferm Nefrol [online]. 2021, vol.24, n.3, pp.262-270.  Epub Nov 08, 2021. ISSN 2255-3517.  https://dx.doi.org/10.37551/s2254-28842021023.

Introduction:

Being an active healthcare worker is a high-risk factor for contracting the SARS-CoV-2 infection. The implementation of vaccination programs is the best option available to solve this problem. In Spain, healthcare professionals have been vaccinated as a matter of priority.

Objective:

To assess, through blood antibody counts, the immunogenicity of SARS-CoV2 vaccines in dialysis personnel and related factors.

Material and Method:

Observational, cross-sectional and multicentric descriptive study.

Results:

167 participants, all vaccinated with RNA vaccines. 15% have previously passed the infection. 96.4% have developed antibodies (mean of 15,776 +/-13,640). Those professionals who have previously passed the infection have a significantly higher average number of antibodies than those who have not (23,532 vs 14,381) (p=0.05). The presence of symptoms such as fatigue, headache, fever, and myalgia is also related with a significantly greater reactivity (p=0.004). There is no significant relationship between reactivity and sex, age, BMI, or workplace.

Conclusions:

Immunogenicity caused by RNA vaccines administered to dialysis personnel has been almost complete. Suffering post-vaccination adverse effects such as fatigue, headaches, fever, nausea, pain, and having previously passed the infection is related to a greater reactivity, manifested by the development of an increased number of antibodies.

Keywords : coronavirus; SARS-CoV-2; vaccine; health care worker; hemodialysis.

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