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Ars Pharmaceutica (Internet)

On-line version ISSN 2340-9894

Abstract

IULIA-BURA, Florina; ORTEGA-MARTINEZ, Elena; RUIZ-MARTINEZ, María Adolfina  and  MORALES-HERNANDEZ, María Encarnación. Design and development of a facial serum with Lactobacillus fermentum CECT 5716. Ars Pharm [online]. 2023, vol.64, n.3, pp.230-242.  Epub Dec 18, 2023. ISSN 2340-9894.  https://dx.doi.org/10.30827/ars.v64i3.27306.

Introduction:

The skin is of all the organs of the body that is directly and constantly exposed to external agents. Hence the importance of providing all the necessary nutrients to keep it healthy, cared for and hydrated. When this does not happen, the skin begins to lose water, becomes dehydrated, and can be seriously injured. With this intention, a moisturizing serum with natural active ingredients has been designed and developed. It has been developed and characterized through various studies. In addition, it includes a strain of the probiotic species Lactobacillus fermentum CECT 5716, as an innovation, to enhance the synergistic effect of the product.

Method:

The cited product is characterized by pH, conductivity, and viscosity measurements to test its stability. Besides it is studied to probiotic viability and consumers’ perception of the product’s efficacy.

Results:

Data extracted from pH and conductivity measurements assure that the topical application of our serum is safe, as it does the consumers’ perception of the product’s efficacy study, offering it a better appearance in terms of smoothness and luminosity. This research has revealed the serum’s pseudoplastic characteristics, optimal for its purpose. Lastly, it has been seen that probiotic viability decreases with time.

Conclusions:

Based on the results we obtained; it can be affirmed that our moisturizing serum is safe and effective in skin hydration, due to the properties of the raw materials incorporated and the competitive mechanism of the probiotics included.

Keywords : Formulation/stability; Serum; Skin physiology/structure; Xerosis; Microbiology; Lactobacillus fermentum.

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