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Revista ORL

On-line version ISSN 2444-7986

Abstract

RODRIGUEZ-GONZALEZ, Marta et al. How to improve the precision of Bethesda System diagnostic categories I and III. Rev. ORL [online]. 2021, vol.12, n.4, pp.313-323.  Epub May 02, 2022. ISSN 2444-7986.  https://dx.doi.org/10.14201/orl.25005.

Introduction and objective:

Fine-needle aspiration (FNA) has a primary role in the diagnosis of thyroid nodules. FNA allows us to differentiate benign lesions from malignant ones in most of the cases. However, management of Bethesda System diagnostic categories I (Nondiagnostic or Unsatisfactory) and III (Atypia of Undetermined Significance or Follicular Lesion of Undetermined Significance) are a clinical challenge. The aim of this work is to expose the options we have to improve the diagnosis of those categories using a multidisciplinary approach, an active follow-up, repeating FNA, applying immunohistochemical and/or molecular technics or even perform a core needle biopsy.

Synthesis: Conclusions:

Some or all of these choices are especially useful to identify category III, but active follow-up or additional FNA are preferred to detect category I.

Keywords : thyroid; fine-needle; bethesda system; molecular; core-biopsy; FNA.

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