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Revista de la Asociación Española de Especialistas en Medicina del Trabajo
On-line version ISSN 3020-1160Print version ISSN 1132-6255
Abstract
ACUNA-CONEJERO, Stephanie Sofia et al. Treatment guidelines for latent tuberculous infection. Rev Asoc Esp Espec Med Trab [online]. 2023, vol.32, n.2, pp.147-157. Epub Oct 30, 2023. ISSN 3020-1160.
Introduction:
Healthcare workers have twice the risk of suffering from tuberculosis. Which has an impact on nosocomial transmission in Health Care Centres (HCC). This highlights the important role played by Occupational Risk Prevention (ORP).
Objectives:
to analyse the treatment guidelines for latent tuberculosis infection in the last 5 years.
Materials and Methods:
Systematic review in MEDLINE with PUBMED, SCOPUS, EMBASE, WOS, Cochrane Library Plus, IBECS, LILACS and CISDOC databases. MeSH “Latent Tuberculosis Infection” and “Latent Tuberculosis/drug therapy”. Quality standards: CONSORT and evidence verification: SIGN system.
Results:
5 clinical trials (n= 14,931) were selected that analysed short regimens compared to Isoniazid monotherapy, with significant differences in favour of short regimens.
Conclusions:
Short guidelines suggest, fewer adverse effects, increased adherence, and higher treatment completion rate.
Keywords : Latent Tuberculosis; Latent Tuberculosis Infection; medication; drugs.
