Abstract

CAICOYA, M.  and  MIRON, J.A.. Lung cancer and smoking in Asturias, Spain: A case-control study. Gac Sanit [online]. 2003, vol.17, n.3, pp.226-230. ISSN 0213-9111.

Objective: Lung cancer in Asturias is 1.4-fold greater than the Spanish average, while the proportion of smokers is similar. The objective of this study was to examine the relationship between lung cancer and smoking in Asturias. Material and methods: We performed a hospital-based, incident case control study. The cases were newly diagnosed lung cancer patients and controls were patients from the surgical wards. Information was sought on smoking, occupational exposures, and demographic variables. The analysis was performed by means of odds ratios (OR). Results: One hundred ninety-seven cases and 196 controls were included in the analysis. The adjusted OR of cigarette smoking was 5.77 (95% CI, 2.96-11.22). The risk increased with the number of cigarettes smoked per day (χ ² = 56.3), the number of packs/year (χ ² = 48.4), and the age at which smoking started (χ ² = 76.5). The OR diminished with the number of years of cessation (χ ² = 39.9). Conclusions: The relationship between smoking and lung cancer in Asturias is similar to that found in other parts of the western world. the magnitude of the OR may explain the frequency of lung cancer in Asturias. Greater efforts should be devoted to controlling this problem.

Keywords : Lung cancer; Case-control; Smoking; Age; Dose-response; Effect of smoking cessation.

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