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Archivos de la Sociedad Española de Oftalmología
Print version ISSN 0365-6691
Abstract
LOPEZ-GARCIA, J.S.; GARCIA-LOZANO, I.; RIVAS, L. and MARTINEZ-GARCHITORENA, J.. Use of autologous serum in ophthalmic practice. Arch Soc Esp Oftalmol [online]. 2007, vol.82, n.1, pp.9-20. ISSN 0365-6691.
Objective: To establish a protocol for the use of autologous serum in the ophthalmic practice. Methods: Personal experience and a literature review. Results: The use of autologous serum, in eye drop form, has been reported as a new treatment for several ocular surfaces diseases. These products have biomechanical and biochemical properties similar to normal tears. They contain components such as fibronectin, vitamin A and growth factors that have an epitheliotrophic effect on the ocular surface epithelial cells. Conclusions: The clinical studies performed showed a variable efficacy, with the preparative process and use of the autologous serum eye drops varying considerably between different studies.
Keywords : Autologous serum; ocular surface; dry eye; corneal epithelium; impression cytology.