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Cirugía Plástica Ibero-Latinoamericana
On-line version ISSN 1989-2055Print version ISSN 0376-7892
Abstract
VITERBO, Fausto; DOMINGUES, María Aparecida C; BROCK, Ryane S and FONSECA, Eduardo. Comparison of the inflammatory reaction induced by facial implants os silicone and polytetrafluoroethylene. Study in rabbits. Cir. plást. iberolatinoam. [online]. 2019, vol.45, n.1, pp.11-17. Epub Feb 27, 2020. ISSN 1989-2055. https://dx.doi.org/10.4321/s0376-78922019000100004.
Background and Objective
The treatment for many facial deformities uses many kinds of autologous grafts or alloplastic materials. Polytetrafluoroethylene (PTFE) has several advantages due to its hydrophobic properties, inducing less inflammatory reaction.
Our study evaluates and compares the inflammatory reaction induced by silicone and PTFE stripes.
Methods
Fragments of silicone and PTFE implants were placed in rabbits ears using an incision and a subcutaneous gap. The histological analysis was made 8 weeks later. The samples were stained with hematoxylin/eosin and classified as chronic inflammatory reaction graduation, the presence of neutrophils, lymphocytes, eosinophils, neoangiogenesis, fibroblasts, edema and presence of bleeding and scar. Samples to microbiological analysis and evaluation of bruise and abs- cess were collected at the moment of sacrifice.
Results
Prevalence of abscess at sacrifice and hematoma during the first weeks were significantly higher (p>0.05) in the silicon group.
Conclusions
PTFE induced as much inflammatory reaction as the silicon but with less abscess and hematoma formation.
Keywords : Silicon; Polytetrafluoroethylene; Facial prostheses; Facial implants.