Abstract

CALDERON, E. et al. Intravenous remifentanil delivered through an elastomeric device versus intramuscular meperidine comparative study for obstetric analgesia. Rev. Soc. Esp. Dolor [online]. 2006, vol.13, n.7, pp.462-467. ISSN 1134-8046.

Objectives: To evaluate the effectiveness and security of remifentanil administered by means of elastomeric infusor with PCA IV compared obstetrical analgesia with intramuscular meperidine in obstetric patients with contraindication for epidural analgesia, Material and Method: 24 patients were randomized, an elastomeric infusor Baxter^® with a capacity of 250 ml was filled with 2.5 mg of remifentanil and a 12 mililiter·h-1, was satarted, (average infusion of 0.025·kg-1·min-1 of remifentanil, and boluses of 5 ml with a time of closing of 30 minutes (Group R) or 1 mg/kg-1 of meperidine and 2.5 mg of haloperidol (Group M) every 4 h by IM route. We valued the intensity of pain each 30 min by means of a visual analogical scale (EVA), time of infusion, boluses administered, level of sedatión by means of scale of the alert status and sedatión evaluated by observer (OAA/S), adverse effects and the Apgar test of new born to 1 and 5 min. Results: There were no differences in the anthropometric data of both groups. The average duration of the infusion in group R was of 280 ± 55 min and the necessities of boluses of 1.2 rescue of ± 1,5. The average dose of intramuscular meperidine in group M was of 120 ± 25 mg. The intensity of the pain during the childbirth was significantly smaller in group R (p<0,05) that group M. The sedatión level was similar in both groups (OAA/S 1-2). The hemodinámics parameters, cardiac rate and arterial pressure remained stable without significant differences between both groups. There was no case of respiratory depression. The satisfaction degree was significantly superior in group R. Conclusion: Remifentanil administered by means of elastomeric system PCA IV provides an analgesic effectiveness superior to the intramuscular meperidine and constitutes an alternative modality to the epidural analgesia without causing respiratory depression or excessive sedation, with an elevated level of maternal satisfaction.

Keywords : Remifentanil; Meperidine; Childbirth; PCA; Obstetrical analgesia.

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