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Revista de la Sociedad Española del Dolor
Print version ISSN 1134-8046
Abstract
GARRIDO, B. et al. Pain animal models and electroacupuncture. Rev. Soc. Esp. Dolor [online]. 2007, vol.14, n.4, pp.296-306. ISSN 1134-8046.
Animal models of pain have permitted in the last decades important advances in neurobiologic research, but biological systems are not exact and there are múltiple factors that can lead to contradictory results. Those difficulties are exacerbated in models addressed to electroacupuncture treatment procedures, as a parametric variability exists for the liberation of mediators, also for the response of biochemical systems manipulated under physiologic or pathological conditions, among other the influence of the stress induced analgesia (SIA). Our purpose is to critically analyze some recent experiments in this field, from authors that have faced these difficulties and still have provided important elements for the clarification of the mechanisms involved in acupuncture analgesia.
Keywords : animal model; pain; nociception; electroacupuncture.