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Revista de la Sociedad Española del Dolor
Print version ISSN 1134-8046
Abstract
TORNERO, C.; HERRERA, J.; MOLA, O. and GALVAN, J.. Transdermal Buprenorphine (Feliben®): new therapeutic option for patients with moderate to severe pain. Rev. Soc. Esp. Dolor [online]. 2012, vol.19, n.6, pp.301-309. ISSN 1134-8046.
This paper summarizes the general characteristics of the opioid system and analgesic mechanisms that have allowed the development of new therapeutic options in the therapy areas of moderate to severe pain of both cancer and noncancer origin. It also summarizes the studies forming together the research program and clinical development (phases I and III) of a new pharmaceutical formulation of buprenorphine transdermal patches, Feliben®, which is compared with other formulations of reference in analgesia. Finally, the current opportunity context that these new formulations have in the management of moderate to severe pain is reviewed.
Keywords : Opioids; Buprenorphine transdermal; Feliben®.