SciELO - Scientific Electronic Library Online

 
vol.24 issue6New pulsed radiofrequency technique for the management of chronic pelvic pain. Report of two casesTreatment with opioids in chronic non-cancer pain: recommendations for safe prescribing author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista de la Sociedad Española del Dolor

Print version ISSN 1134-8046

Abstract

AMEZCUA-HERNANDEZ, V.; GARCIA, J.  and  VALDIVIA, J.. Immediate-release fentanyl as coadyuvant for control the side effects off immunotherapy. Clinical case. Rev. Soc. Esp. Dolor [online]. 2017, vol.24, n.6, pp.309-312. ISSN 1134-8046.  https://dx.doi.org/10.20986/resed.2017.3589/2017.

The scientific advance and the appearance of immunotherapy in oncology, requires to know both its results in the form of survival, and the toxicity that this contributes.

Pharmacological stimulation of the immune system can cause distortions in the regulation of the immune system and alter the process of immune tolerance, favoring the appearance of excessive autoimmune reactions against healthy organs.

Autoimmune colitis is an immunorelated event that usually courses with diarrhea. Although the treatment axis is corticoids, it is not always possible to control the adverse effect or the pain that, sometimes, these treatment cause. In our case, the use of fast-acting fentanyl for pain control was able to act as a coadjuvant to the immunosuppressive treatment, slowing the intestinal transit and, consequently, favoring the control of the colitis.

Keywords : Immunotherapy; medical oncology; colitis; autoimmunity; diarrhea; immediate release fentanyl.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )