Abstract

FERNANDEZ VENTUREIRA, Víctor et al. Hypotonic-hyporesponsive episode in early childhood. Rev Pediatr Aten Primaria [online]. 2019, vol.21, n.84, pp.379-381.  Epub May 25, 2020. ISSN 1139-7632.

Hypotonic-hyporesponsive episode is known as a rare vaccine adverse event in early childhood, mainly associated with antipertussis component. It is characterized by a sudden onset of reduced muscle tone, hyporesponsiveness and change of skin color (paleness or cyanosis). Because of being a little-known event with unknown pathophysiological mechanisms and a diagnosis by exclusion, its knowledge by the health professional takes on even greater importance for making an adequate differential diagnosis, avoiding unnecessary tests and preventing fear of vaccination in the society.

Keywords : Drug-related side effects and adverse reactions; Hypotonic-hyporesponsive episode; Vaccination.

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