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Revista de la OFIL
On-line version ISSN 1699-714XPrint version ISSN 1131-9429
Abstract
SANCHEZ-RUBIO-FERRANDEZ, L et al. Cost avoided in drugs derived from the participation of patients in oncology clinical trials. Rev. OFIL·ILAPHAR [online]. 2022, vol.32, n.3, pp.229-233. Epub Sep 25, 2023. ISSN 1699-714X. https://dx.doi.org/10.4321/s1699-714x2022000300003.
Introduction:
Cancer is the second leading cause of death globally. About one in six deaths is due to this disease. The economic impact of cancer is increasing and has a high prevalence leading to high economic burden for the Health System mainly related to oncologic pharmacotherapies. The objective of this study is to calculate pharmaceutical expenditure savings as a consequence of patient's involvement in Oncology Clinical Trials.
Material and methods:
Retrospective observational study. In order to determine savings in oncology drugs, cancer treatments of patients participating in oncology clinical trials in April 2018 in a tertiary hospital in Spain were analyzed. Taking into account that the sponsor of the clinical trial provides the study medication free of charge, the costs savings were calculated comparing with the cost that would have supposed to treat the patient if they would have been received was standard regime for the type of tumor under study in clinical practice.
Results:
The cost avoided in the 50 oncology clinical trials analyzed was 1,564,943.59 euros. The average avoided cost per OCT was 31,298.87 euros, and the average avoided cost per patient was 10,096.41 euros.
Conclusions:
The participation of patients in oncology clinical trials provides an important economic saving, since it reduces the costs in the acquisition of medicines when they are provided free of charge by the sponsor of the study.
Keywords : Avoided cost; clinical trial; oncology.