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Journal of Negative and No Positive Results
On-line version ISSN 2529-850X
Abstract
VILLAR-INAREJOS, Mª José et al. Evaluation of chronic pain treatments in arthrosis. JONNPR [online]. 2021, vol.6, n.8, pp.997-1033. Epub Dec 25, 2023. ISSN 2529-850X. https://dx.doi.org/10.19230/jonnpr.3998.
Osteoarthritis is a degenerative disease of the joints, with a prevalence of 10% in Spain, being the leading cause of disability. The main symptom, and towards which most of the therapies are directed, is pain. The objective of this bibliographic review is to know how this disease can be treated, which are the therapies under investigation, showing example studies that help us draw conclusions. It is done through the consultation of different bibliographic sources. There is a non-pharmacological treatment based on the health education of the patient, including practices such as acupuncture or ultrasounds, certain foods, physical exercise and medicinal plants. There is also a pharmacological treatment with oral and fast-acting analgesics and anti-inflammatories, to relieve pain, such as paracetamol and NSAIDs, weak opioids and strong opioids that are used transdermally in this pathology; and finally capsaicin or NSAIDs topically. There are disease-modifying drugs called SYSADOA slow-acting, such as chondroitin sulfate, glucosamine sulfate, and diacerein. Sometimes joint infiltrations are made with hyaluronic acid and corticosteroids to act locally and be more effective, and even sometimes with botulinum toxin and other substances that we will see. Surgical treatment is another alternative, but we will not talk about it in our work. Treatment of osteoarthritis is primarily focused on relieving pain for patients and improving their quality of life.
Keywords : Osteoarthritis; Pain treatment; exercise; anti-inflammatories.