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Revista de la Asociación Española de Especialistas en Medicina del Trabajo
On-line version ISSN 3020-1160Print version ISSN 1132-6255
Abstract
SOARES, Jorge et al. Evaluation of the immunological response to three doses of the Hepatitis B vaccine in workers of a Portuguese university Hospital. Rev Asoc Esp Espec Med Trab [online]. 2021, vol.30, n.1, pp.57-62. Epub May 10, 2021. ISSN 3020-1160.
Objectives:
evaluate the response to three doses of the Hepatitis B vaccine in healthcare workers. Analyze its association with age, gender, smoking, body mass index (BMI), presence of chronic diseases and time elapsed between vaccination and the measurement of AcHBs.
Material and Methods:
observational, cross-sectional study. Sample of workers from a Portuguese University Hospital who measured AcHBs in 2018 and who had a complete vaccination scheme. The individual clinical process was consulted. The Mann-Whitney and Chi-square test were applied and a significance level of 5% was accepted.
Results and Conclusions:
We analyzed the results of 181 workers, mean age 32.99 years (min. 20 - max. 64), the majority women (76.80%). The AcHBs was positive in 140 (77.35%) and negative in 41 (22.65%). The presence of chronic diseases showed a statistically significant association with negative AcHBs after a complete vaccination scheme.
Keywords : Hepatitis B; Hepatitis B Antibodies; Hepatitis B Vaccine; Healthcare Workers.
