My SciELO
Services on Demand
Journal
Article
Indicators
Cited by SciELO
Access statistics
Related links
Cited by Google
Similars in SciELO
Similars in Google
Share
Revista de Diagnóstico Biológico
Print version ISSN 0034-7973
Abstract
FERNANDEZ-GARCIA, N. et al. Resultados de las peticiones de anticuerpos tiroideos en un Hospital Provincial de Castilla-León . Rev Diagn Biol [online]. 2001, vol.50, n.4, pp.197-199. ISSN 0034-7973.
Objectives: To evaluate if simultaneous determination of both TPOAb and TgAb is clinically more adequate than single determination of TPOAb. Materials and methods: quantification using a microplate immunoassay of 1236 samples in which an autoimmune thyroid protocol was requested (TPOAb and TgAb). Results: Patients were classified by positive or negative results of both TPOAb and TgAb as follows: TPOAb (-) - TgAb (-), 61.4%; TPOAb (+) - TgAb (-), 22.8%; TPOAb (+) - TgAb (+), 13.6% and TPOAb (-) - TgAb (+), 2.2%; a higher prevalence of positive results was observed in women in comparison to men 30% n 6.3% for TPOAb and 13.6%n 2.2% for TgAb. Conclusions: the simultaneous protocol (TPOAb and TgAb) for thyroid autoimmune diseases have no more clinical usefulness than a single protocol (TPOAb). The first one protocol must be reserved for concrete clinical situations as differentiated thyroid cancer whereas the single one (TPOAb) could be implanted on routine.
Keywords : antithyroid peroxidase antibodies (TPO-Ab); antithyroglobulin antibodies (Tg-Ab); TSH-receptor antibodies (TR-Ab); hyperthyroidism; hypothyroidism.