Abstract

CORELLA, Dolores; BARRAGAN, Rocío; ORDOVAS, José Mª  and  COLTELL, Óscar. Nutrigenetics, nutrigenomics and Mediterranean diet: a new vision for gastronomy. Nutr. Hosp. [online]. 2018, vol.35, n.spe4, pp.19-27.  Epub Sep 28, 2020. ISSN 1699-5198.  https://dx.doi.org/10.20960/nh.2120.

Both nutrigenetics and nutrigenomics are disciplines that form part of what is known as Nutritional Genomics, which, in the widest sense, provides the framework for integrating different omics with food and nutrition sciences.

After decades of nutrigenetic and nutrigenomic studies, there is a large enough amount of knowledge to consider its application in so-called precision nutrition. This new discipline seeks to take into account the particular characteristics of the individual in order to provide the best diet for preventing or treating a disease. Omic markers are considered to be of importance to that personalization. There are many foods, nutrients and dietary patterns that have been researched in nutrigenetics and nutrigenomics, including the Mediterranean Diet pattern.

Despite heterogeneity in defining the Mediterranean Diet, there are various studies that show that the Mediterranean Diet can interact with the genome, so reducing the risk of disease in the most genetically susceptible individuals. Likewise, several studies have recently been revealing the mechanisms through which the Mediterranean Diet may exercise this protective effect. Understanding genetic susceptibility, epigenetic mechanisms, the influence of the metabolome and other omics in more detail may be important in gastronomy, understood as the practice of selecting, cooking and eating food.

This omic influence can not only be found in health-disease phenotypes, but also in food taste and smell perception and preferences for certain dishes. Considering all of these together may contribute to an increase in enjoying and at the same time pursuing healthy eating.

Keywords : Nutrigenetics; Nutrigenomics; Nutritional genomics; Mediterranean diet; Taste; Precision nutrition; Bioinformatics.

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