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Pediatría Atención Primaria
Print version ISSN 1139-7632
Abstract
VALDES ALONSO, MC et al. Thyroid diseases in adolescents with type 1 diabetes mellitus. Rev Pediatr Aten Primaria [online]. 2017, vol.19, n.75, pp.249-257. ISSN 1139-7632.
Introduction:
the type 1 diabetes mellitus is related with thyroid alterations. Objective: to determine the behaviour of thyroid diseases in pediatric patients with type 1 diabetes mellitus.
Material and method:
descriptive cross-sectional study in 56 adolescents with diagnostic of type 1 diabetes mellitus assisted in the service of Endocrinology of the Juan Manuel Márquez hospital in the period between October 2015 and October 2016. The variables in study were: age, sex, time of evolution of the diabetes mellitus, nutritional state, thyroid function and autoimmune thyroid disease. The qualitative variables were statistically sescribed by absolute and relative frequencies; the association among the categorical variables was explored with the χ2 test and Fisher's exact probability. In all the statistical tests, it was considered a significance level of alpha equal to 0.05.
Results:
46.29% of the studied patients presented autoimmune thyroid disease; of them, 33.33% were female. The highest degree of thyroid dysfunction was present in older patients (36.0%), with normal weigh (68.0%) and time of evolution of the diabetes mellitus among 5-9 years (52.0%). 32.0% vs 80.0% of the patients presented antithyroglobulin antibodies and antithyroperoxidase antibodies respectively, being related this last one with the age and the time of evolution of the diabetes mellitus.
Conclusions:
thyroid dysfunction was presented in the patients with autoimmune thyroid disease related to the age and the time of evolution of the type 1 diabetes mellitus. The antithyroperoxidase antibodies were related with the age and the time of evolution of type 1 diabetes mellitus.
Keywords : Thyroid diseases; Autoimmune thyroiditis; Type 1 diabetes mellitus.