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Nutrición Hospitalaria
versión On-line ISSN 1699-5198versión impresa ISSN 0212-1611
Resumen
TELLO-PALMA, Edith et al. Effects of microencapsulated and heme iron supplementation on the recovery of hemoglobin levels in iron-depleted rats. Nutr. Hosp. [online]. 2022, vol.39, n.6, pp.1357-1363. Epub 20-Feb-2023. ISSN 1699-5198. https://dx.doi.org/10.20960/nh.04075.
Introduction:
one of the causes of Nutritional anemia is that the amount of iron absorbed is insufficient to meet the body's needs.
Objective:
to determine the effects of microencapsulated and heminic iron supplementation to increase hemoglobin levels and body weight in iron-depleted rats.
Methods:
a randomized experimental study was designed. Four study groups were formed. Control group (GC), experimental group (GE1) (MC microencapsulated iron supplementation), experimental group 2 (GE2) (heminic iron supplementation) and experimental group 3 (GE3) (MC + heminic iron supplementation). A dry powdered diet containing all normal nutrients except iron was fed to the four groups for 15 days (three times a day). Weight, length and hemoglobin (Hb) were evaluated at pre- and post-test under similar conditions.
Results:
in Hb, no significant differences were observed in the CG (p = 0.225), despite a -9.6 % decrease in the post-test. GE1 significantly increased hemoglobin (14.3 %, Hb 2.1 g/dl) and body weight (21.6 %, 25.8 g) (p < 0.05) in the post-test. Similarly, GE2 significantly increased hemoglobin (14.5 %, Hb 2.1 g/dl) and body weight (44.5 %, 52.3 g) (p < 0.05). However, in GE3, despite significantly increasing weight (30.2 %, 35.2 g), the increase in hemoglobin levels was similar to what occurred in GE1 and GE2 groups (increasing by 14.5 % and Hb 2.2 g/dl). There were no significant differences in rat length between pre- and post-test in the four groups.
Conclusion:
these RESULTS suggest that heme iron together with quinoa and cañihua flour could be exploited as a new safe and efficient iron supplement compared to microencapsulated iron, given its higher iron bioavailability and its ability to increase body weight.
Palabras clave : Supplementation; Heme iron; Microencapsulated; Rats.