Background and objective.

Peripheral nerve injury, in all its mechanisms, is a frequent event in the general population. There are diferent methods of repairing it, however there is not enough research on the most effective graft.

The objective of this study is to determine the superiority of the combination of polyethylene glycol in polytetrafluoroethylene tubes as a graft versus its isolated use and an autograft.

Methods.

Experimental study of cases and controls using Wistar rats that were induced, under sedation, nerve injury by extracting a nerve graft from the sciatic nerve and its subsequent repair, divided into 3 groups: autograft, polytetrafluoroethylene graft and polytetrafluoroethylene graft with polyethylene glycol.

Results.

Eight histopathological variables were analyzed and a total axon count was made, finding a greater number in the autograft samples. Among the clinical variables, limb deformity, macroscopic muscular atrophy and walking disturbance were analyzed, showing the group of the combination of materials an excellent evolution in the 3 categories.

Conclusions.

The clinical recovery of the operated limb in the group where the combination of the studied materials was used was notably superior, in addition to the observation of much better axonal organization, indicating a superiority of this combination with respect to the other groups evaluated.

        · resumen en Español     · texto en Español     · Español ( pdf )