Mi SciELO
Servicios Personalizados
Revista
Articulo
Indicadores
Citado por SciELO
Accesos
Links relacionados
Citado por Google
Similares en SciELO
Similares en Google
Compartir
Archivos de la Sociedad Española de Oftalmología
versión impresa ISSN 0365-6691
Resumen
BARRIO-MANSO, I. del et al. Creutzfeldt - Jakob presenting with isolated visual symptoms: the Heidenhain variant. Arch Soc Esp Oftalmol [online]. 2010, vol.85, n.10, pp.341-344. ISSN 0365-6691.
Clinical case: We report the case of a 67 year old female complaining of decreased vision and diagnosed with the Heidenhain variant of sporadic Creutzfeldt-Jakob disease. Her past medical history was unremarkable. She died less than three months after the onset. Discussion: The Heidenhain variant of sporadic Creutfeld-Jakob disease should be suspected in patients suffering from early visual disturbances, unremarkable ophthalmic examination, and subsequent rapid decline of their cognitive function. A complete neurological exam including electroencephalogram recordings and magnetic resonance is mandatory. These patients share a common genotype (PRNP codon 129 MM) associated with a clinically typical disease course.
Palabras clave : Creutzfeldt-Jakob disease; Heidenhain variant; Spongiform encephalopathy; Prion protein; Visual acuity loss; Visual function.