Resumen

FLORES-VILLALBA, Eduardo et al. Unusual presentation of Gilbert disease with high levels of unconjugated bilirubin: report of two cases. Rev. esp. enferm. dig. [online]. 2016, vol.108, n.4, pp.228-230. ISSN 1130-0108.

Gilbert's syndrome is a benign condition characterized by asymptomatic sporadic episodes of jaundice, due to a mild unconjugated hyperbilirubinemia caused by a deficiency in bilirubin glucoronidation. Under certain physiologic or pathologic events, bilirubin level rises but according to literature it does not reach out more than 3 mg/dl. We report 2 cases of Gilbert's syndrome, genetically tested, which presented with bilirubin levels above 6 mg/dl without any trigger or coexisting condition. In conclusion, bilirubin levels higher than 6 mg/dl in Gilbert syndrome are rare, hemolytic and other metabolism diseases must be ruled out, and genetic testing may be necessary in some cases.

Palabras clave : Gilbert's syndrome; Jaundice; Unconjugated hyperbilirubinemia.

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