Objectives:

To analyze the health-related quality of life (HRQoL) in patients with advanced chronic kidney disease in pre-dialysis and the relationship with the dependency for the instrumental activities of daily living (IADL).

Material and Method:

A descriptive and cross-sectional study was carried out in the Nephrology Service of the Reina Sofía University Hospital in Córdoba. It was a non-probability accidental sampling. The following questionnaires were used: KDQOL-SF to analyze HRQoL and Lawton y Brody for IADL dependency.

Results:

105 patients on pre-dialysis were studied with an age of 67,8±15,7 years and 35 women (33,3%). With regards to the KDQOL, the most affected dimensions were Changes in health status, Work situation, Burden of kidney disease, General health, Vitality and Physical role. 57.1% of the participants had some degree of dependence for the instrumental activities of daily life. Patients with a higher degree of dependency had worse scores in the dimensions Effects of kidney disease, Work situation, Cognitive function, Sleep, Physical function, Physical role, Pain, Social function and Vitality.

Conclusions:

Pre-dialysis patients have a decreased health-related quality of life in the dimensions Changes in health status, Work situation, Burden of kidney disease, General health, Vitality and Physical role. More than half of the participants show some type of dependency to carry out the instrumental activities of daily life.