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Revista de la Asociación Española de Especialistas en Medicina del Trabajo

versión On-line ISSN 3020-1160versión impresa ISSN 1132-6255

Resumen

DE LA FUENTE-MARTIN, José Manuel et al. Need for immunological determination of Quantiferon (Interferon-gamma Relase-Assay) for the diagnosis of latent tuberculous infection. Rev Asoc Esp Espec Med Trab [online]. 2022, vol.31, n.3, pp.254-259.  Epub 12-Dic-2022. ISSN 3020-1160.

Introduction:

Tuberculosis is a major public health problem, first cause of death in adults infected with a single infectious agent. We will differentiate active tuberculosis disease from latent tuberculosis infection. The biological control of the initial health examination establishes whether the worker is a carrier of LTTI to differentiate him/her from a possible subsequent contagion at work.

Objectives:

General objective to estimate the validity of Mantoux/Booster and Quantiferon as diagnostic tests for LTTI. Specific objective: To define the cases diagnosed as ITL.

Material and Methods:

Collection of data from the clinical-work histories of newly hired personnel, from the Zamora Health Area, years 2018-2021, imported into a database, qualitative/quantitative descriptive study is performed.

Results:

29.1% of the workers studied were tuberculin positive; 10.3% were Quantiferon positive. We diagnosed 159 cases of ITL.

Conclusion:

The most accurate technique to diagnose ITL is the determination of Quantiferon.

Palabras clave : Tuberculosis; Latent Tuberculous Infection; Tuberculin test; Quantiferon.

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