Mi SciELO
Servicios Personalizados
Revista
Articulo
Indicadores
Citado por SciELO
Accesos
Links relacionados
Citado por Google
Similares en SciELO
Similares en Google
Compartir
Archivos de la Sociedad Española de Oftalmología
versión impresa ISSN 0365-6691
Resumen
BENITEZ-HERREROS, J. et al. Endothelial cells analysis after intraoperative mitomycin-C adjuvant pterygium simple excision surgery: a pilot study. Arch Soc Esp Oftalmol [online]. 2010, vol.85, n.1, pp.11-15. ISSN 0365-6691.
Purpose: To study the effects of mitomycin-C (MMC) on the corneal endothelium after pterygium surgery. Methods: Prospective, interventional, nonrandomized, observer-masked study. Twenty patients (20 eyes) with primary pterygium underwent surgery with pterygium simple excision followed by 0.02% MMC application for 1 minute. Preoperative, 10-day, 1-month and 3-month postoperative specular microscopy were performed. Mean cell density, coefficient of variation of mean cell area and percentage of hexagonal cells were measured. Results: Mean endothelial cell densities before and 3 months after surgery were 2,240.37 SD 347.92 cells/mm2 (range: 1,020 to 2,703) and 2,283.86 SD 425.13 cells/mm2 (range: 1,001 to 2,837), respectively. Mean coefficient of variation before and 3 months after surgery were 32.63 SD 4.65 (range: 22 to 48) and 33.00 SD 4.75 (range: 23 to 51), respectively. Mean percentage of hexagonal cells before and 3 months after surgery were 54.58 SD 6.60 (range: 46 to 71) and 55.26 SD 8.89 (range: 38 to 76), respectively. No statistically significant differences were found in any of the parameters studied when compared to the preoperative values. Conclusions: A single intraoperative application of 0.02% MMC for 1 minute during pterygium simple excision surgery does not seem to cause substantial changes in corneal endothelial cell density at 3 months.
Palabras clave : Corneal endothelium; Specular microscopy; Mitomycin-C; Pterygium; Corneal toxicity.