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Ars Pharmaceutica (Internet)
versión On-line ISSN 2340-9894
Resumen
BAYONA-CABALLERO, María; ALAYO-ZAVALETA, Judith; LOMBARDI-PEREZ, César y MARIN-TELLO, Carmen. The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays. Ars Pharm [online]. 2019, vol.60, n.4, pp.213-218. Epub 09-Mar-2020. ISSN 2340-9894. https://dx.doi.org/10.30827/ars.v60i4.10226.
Introduction:
To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue.
Method:
Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study.
Results:
Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia.
Conclusions:
Wheat germ diet may have a radioprotective effect on rat myocardium.
Palabras clave : Triticum; X-Rays; heart.