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Revista de Osteoporosis y Metabolismo Mineral

versión On-line ISSN 2173-2345versión impresa ISSN 1889-836X

Rev Osteoporos Metab Miner vol.15 no.1 Madrid ene./mar. 2023  Epub 29-Mayo-2023

https://dx.doi.org/10.20960/revosteoporosmetabminer.00009 

IMAGE IN OSTEOLOGY

Saber tibia

Jesús Rubio-Úbeda2  , Inmaculada Jiménez-Moleón2  , Enrique Raya-Álvarez2 

2Rheumatology Service. Hospital Universitario Clínico San Cecilio. Granada, Spain

CASE REPORT

A 91-year-old woman presented with a 6-month history of pain in the right tibial region, associated with bone deformity and progressive difficulty in walking. Physical examination confirmed these findings, also highlighting an increase in local temperature in the right tibial region.

A basic analytical study with biochemistry and complete blood count was carried out, including phosphocalcic metabolism parameters and bone remodeling markers. Raised levels of alkaline phosphatase (AP) in serum (141 U/L [N = 30-120]) were observed, as well as elevation of bone formation markers (type I collagen amino-terminal propeptide [PINP] 166 ng/mL, [N = 20.2-76.3]) and bone resorption markers (β-CrossLaps [β-CTX] 0.042 ng/mL [N = 0.000-0.028] and C-terminal telopeptide [ICTP] 1.28 ng/mL [N = 0.556-1]).

Imaging included X-rays of long bones, pelvis, thoracolumbar spine and skull which revealed a characteristic image of saber shin at the level of the right tibia (Figs. 1-3 3), and bone scan with 99mTc-HDA (Fig. 4). Given these test results, and after only finding alterations (both structural and metabolic) at the level of the right tibia, the patient was finally diagnosed with monostotic Paget’s disease of bone.

DISCUSSION

The case presented is paradigmatic of Paget’s bone disease with a saber tibial deformity. In our case, late diagnosis takes on a special meaning insofar as the observed deformity must have developed over decades without having been diagnosed until then. These highlights the importance of detecting deformities of the musculoskeletal system in any basic examination carried out in a consultation to avoid both its progression and complications derived from the disease itself.

CLINICAL IMAGES

Figure 1. X-ray of the right femur and femorotibial joint: the contrast between the fine reticular trabecular pattern of the femur and the coarse and aberrant trabeculation observed in the tibial plateau stands out. Femorotibial and patellofemoral osteoarthritis. As an incidental finding, calcification of the femoropopliteal artery. 

Figure 2. Radiographs of the right tibia. Saber tibia: increased cortical and periosteal thickness, with a coarse and disordered trabecular pattern, as well as a large tibial deformity, which curves laterally with a saber appearance. 

Figure 3. Radiographs of the right tibia. Saber tibia: increased cortical and periosteal thickness, with a coarse and disordered trabecular pattern, as well as a large tibial deformity, which curves laterally with a saber appearance. 

Figure 4. Whole-body bone scan with 99mTc-HAD. Uptake of moderate/severe intensity is observed in the right tibia. In the rest of the skeleton, a more diffuse and less intense deposit can be seen in the shoulders, elbows, wrists and left knee with degenerative characteristics. 

Rubio Úbeda J, Jiménez Moleón I, Raya Álvarez E. Saber tibia. Rev Osteoporos Metab Miner 2023;15(1):40-42

Received: June 24, 2022; Accepted: October 10, 2022

Conflict of interests:

the authors declare no conflict of interest.

Creative Commons License This is an open-access article distributed under the terms of the Creative Commons Attribution License