Resumo

GRANDE-MONTALVO, Tanilu C.  e  FAURA-BERRUGA, Cristina. A highly destructive tumour. Rev Clin Med Fam [online]. 2014, vol.7, n.2, pp.137-140. ISSN 2386-8201.  https://dx.doi.org/10.4321/S1699-695X2014000200009.

The basal-cell carcinoma is the most frequent cancer in human beings. It is characterized by being locally invasive and slow-growing. We present the case of a patient with basal cell carcinoma which caused a marked destruction of the nasal region, for which reason he could not be treated surgically or with radiotherapy. For this type of patient, a new innovative therapy is proposed: Vismodegib, a molecule which inhibits the spreading of the tumour and which has signified a great advance in the management of these patients.

Palavras-chave : Basal-cell carcinoma; Cutaneous destruction; Vismodegib; Hedgehog pathway.

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