SciELO - Scientific Electronic Library Online

 
vol.32 número4Manejo de altas dosis de metotrexato en un caso de leucemia aguda linfoblásticaSíndrome de lisis tumoral en paciente hematológico índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Revista de la OFIL

versão On-line ISSN 1699-714Xversão impressa ISSN 1131-9429

Resumo

GIL-SIERRA, MD  e  BRICENO-CASADO, MP. Multidisciplinary clinical management of complex patient with Crohn's disease and paradoxical psoriasiform reaction. Rev. OFIL·ILAPHAR [online]. 2022, vol.32, n.4, pp.403-405.  Epub 23-Out-2023. ISSN 1699-714X.  https://dx.doi.org/10.4321/s1699-714x20220004000016.

Crohn's disease is an inflammatory disease of any part of the gastrointestinal tract. This pathology can present systemic and extra-intestinal manifestations. Biological drugs are used in patients with moderate-severe Crohn's disease refractory to previous therapies. Paradoxical psoriasiform reactions have been associated with biological treatments with an anti-tumor necrosis factor (antiTNF α) mechanism, such as adalimumab. On the other hand, ustekinumab has been described as an effective therapeutic alternative with a favorable safety profile in patients with comorbidities and/or hypersensitivity reactions to other drugs. The multidisciplinary collaboration of different healthcare professionals allows the identification of infrequent adverse events –such as paradoxical psoriasiform reaction– and therapeutic optimization of complex patients. This case describes the clinical and therapeutic experience of a multidisciplinary collaboration in a complicated patient diagnosed with Crohn's disease and a paradoxical psoriasiform reaction secondary to adalimumab.

Palavras-chave : Ustekinumab; comorbidity; adverse reaction; psoriasiform reaction.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )