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Revista de la Asociación Española de Especialistas en Medicina del Trabajo
versão On-line ISSN 3020-1160versão impressa ISSN 1132-6255
Resumo
DE LA FUENTE-MARTIN, José Manuel et al. Need for immunological determination of Quantiferon (Interferon-gamma Relase-Assay) for the diagnosis of latent tuberculous infection. Rev Asoc Esp Espec Med Trab [online]. 2022, vol.31, n.3, pp.254-259. Epub 12-Dez-2022. ISSN 3020-1160.
Introduction:
Tuberculosis is a major public health problem, first cause of death in adults infected with a single infectious agent. We will differentiate active tuberculosis disease from latent tuberculosis infection. The biological control of the initial health examination establishes whether the worker is a carrier of LTTI to differentiate him/her from a possible subsequent contagion at work.
Objectives:
General objective to estimate the validity of Mantoux/Booster and Quantiferon as diagnostic tests for LTTI. Specific objective: To define the cases diagnosed as ITL.
Material and Methods:
Collection of data from the clinical-work histories of newly hired personnel, from the Zamora Health Area, years 2018-2021, imported into a database, qualitative/quantitative descriptive study is performed.
Results:
29.1% of the workers studied were tuberculin positive; 10.3% were Quantiferon positive. We diagnosed 159 cases of ITL.
Conclusion:
The most accurate technique to diagnose ITL is the determination of Quantiferon.
Palavras-chave : Tuberculosis; Latent Tuberculous Infection; Tuberculin test; Quantiferon.