Resumo

CLAUDET ANGULO, P.C. et al. Efficacy of JAL 90458 in the regrowth of plaque in patients with orthodontic braces. Av Odontoestomatol [online]. 2013, vol.29, n.5, pp.245-253. ISSN 2340-3152.

Introduction. The objective was test the efficacy of JAL 90458 on the regrowth of plaque in patients with orthodontic braces. Material and methods. A total of 16 subjects (11 women and 5 men) between the ages of 12 and 39 took part in this study. The study was conducted under clinical trial conditions, double blind, parallel and randomized in balanced groups using a plaque regrowth design. The subjects had a professional teeth-cleaning and were instructed to not use any kind of oral hygiene measures for the next four days, using only the gel that had been assigned to them. We took into account the following parameters: the Quigley - Hein plaque index, modified by Turesky (QHPI-T), Plaque-Bracket Index (PIb) and the Bleeding on Probing Index (BOP). Analysis of the data was done using a Student´s t-test, Fisher´s exact test and Pearson´s correlation coefficient. Results. Statistically significant differences between the JAL 90458 group and the control gel group were obtained in the QHPI-T (2.52±0.57 vs 1.78±0.79, p<0.05), as well as in the PIb (2.04±0.73 vs 1.27±0.59, p<0.05), and BOP (1.24±0.20 vs 0.48±0.24, p<0.05). There was a high correlation between the PIb and the QHPI-T (r=0.87, p<0.01). The linear regression equation to predict the value of the QHPI-T using the PIb was: QHPI-T=0.568+0.956 * PIb. Discussion. The application of JAL 90458 in patients with orthodontic braces was shown to be effective in the diminishing the regrowth of bacterial plaque. We did not detect any clinically relevant side effect.

Palavras-chave : Mouthrinses; triclosan; dental plaque; orthodontic braces; clinical trials; plaque index.

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