SciELO - Scientific Electronic Library Online

 
vol.19 número7Mejor resultado del ajuste de la dosis de digoxina en ancianos si se tiene en cuenta que tanto la eliminación como el volumen de distribución del fármaco disminuyen cuando se reduce la función renalTipos evolutivos de hipertensión portal prehepática en la rata índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Anales de Medicina Interna

versão impressa ISSN 0212-7199

Resumo

GIMENO ORNA, J. A.; BONED JULIANI, B.; LOU ARNAL, L. M.  e  CASTRO ALONSO, F. J.. Mortality in a cohort of patients with type 2 diabetes mellitus of Alcañiz area, Spain. An. Med. Interna (Madrid) [online]. 2002, vol.19, n.7, pp.14-18. ISSN 0212-7199.

Objective: The aim of this study was to compare the mortality rate of type 2 diabetic patients with the mortality rate of the background population. Also was assessed the impact of baseline variables on mortality.  Methods: Prospective cohort study. Patients with type 2 diabetes were included from june 1994 to june 1998. The life status was ascertained on october 2001. Excess mortality, compared with the background population, was assessed in terms of standardised mortality ratio (SMR) for the whole group, for males and for females. The Cox´s model was used to investigate the influence of baseline risk factors on mortality.  Results: 463 patients were included. The mean follow-up was of 5 years. The life status was acertained for the 99% of the cohort. The mortality rate of the whole group was 21.75 per 1000 (31.4 per 1000 males and 16.4 per 1000 females). The SMR of the whole group was 147% (IC 95%: 109 - 194; p<0.05), the SMR of males 167% (IC 95%: 107 - 246; p<0.05) and the SMR of females 147% (IC 95%: 95 - 217; p=ns). The independent predictors of early mortality on multivariate survival analysis were age (HR = 1.13; IC 95%: 1.08-1.18; p<0.0001) and proteinuria (HR = 4.72; IC 95%: 2.15 - 10.35; p=0.0001) .  Conclusions: Diabetic patients in our population have increased their mortality risk in 47%. The main risk factor of mortality was the presence of proteinuria. 

Palavras-chave : Type 2 diabetes mellitus; Mortality; Standardized mortality ratio; Proteinuria.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons