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Farmacia Hospitalaria
versão On-line ISSN 2171-8695versão impressa ISSN 1130-6343
Resumo
SUAREZ-ARTIME, Pedro et al. Medication adherence to obeticholic acid: a real-world experience using medication event monitoring systems. Farm Hosp. [online]. 2022, vol.46, n.4, pp.260-264. Epub 23-Set-2022. ISSN 2171-8695. https://dx.doi.org/10.7399/fh.11824.
Objective:
We designed a clinical study to analyze patterns of adherence to obeticholic acid, factors influencing the adherence and potential correlation with treatment efficacy by using MEMS® cap in practice daily.
Method:
A multicenter prospective observational study of patients with primary biliary cholangitis. Adherence will be measured by MEMS® cap, pill count, and patient-reported outcomes during 3 months. The quality of life will be self-reported using the Chronic Liver Disease Questionnaire test, European Quality of Life 5-Dimension Questionnaire test and Itch Severity Scale.
Conclusions:
We expect to clarify if there is correlation between adherence with treatment efficacy and to identify causes for poor compliance and introduce measures to reduce its prevalence.
Palavras-chave : Medication adherence; Medication event monitoring systems; Obeticholic acid; Liver Cirrhosis, Biliary; Quality of life.
