Antecedents and objectives:

The coronavirus disease 2019 (COVID-19) has spread worldwide to be reported to date 3.446.072 cases in Spain which causes a very challenging situation for the Spanish Health Care System. This study aims to describe the adjustments, analytical and microbiological parameters of patients clinically diagnosed with SARS-CoV-2 infection in the first weeks of the pandemic.

Material and methods:

A retrospective observational study. 180 patients have been included in the study since they were treated by our emergency unit for a period beginning on March 9 ending on April 24, 2020. They were clinically diagnosed with COVID-19. The study provides analysis on their demographic, analytical and microbiological data.

Results:

The average patient was 64 years old and 60.6 % were men. 86.1 % obtained a positive RT-PCR, 3.9 % a negative one. The 10 % left provided an inconclusive result. IgG antibodies were detected in 84.4 % and IgM antibodies in 85.6 %. 26.0 % of our patients suffered from lymphopenia and 13.6 % thrombocytopenia. 67.4 % and 77.3 % had respectively D-dimer and fibrinogen levels above the normal range. High serum levels of ALT (45.0 %), AST (30.5 %), LDH (71.9 %), C-reactive protein (74.5 %), and procalcitonin (11.9 %) were reported. High ferritin concentrations were found in 75.2 %.

Conclusions:

The alterations observed in the analytical parameters are the most common in cases of COVID-19. These high level rates have been considered prognostic markers of severity and mortality.