Introduction:

The infectious disease caused by the SARS-CoV-2 virus has posed a serious public health problem in the general population. For individuals with chronic kidney disease, a higher risk of developing severe complications and mortality has been observed

Objective:

To identify scientific evidence related to mortality from SARS-CoV-2 in individuals with chronic kidney disease.

Methodology:

An integrative review was conducted by searching the Scopus, EBSCO, PubMed (which also includes the Medline database), Science Direct, Scielo, Lilacs, and Embase databases.

Results:

A total of 14 articles were obtained and reviewed. These articles were written in English and Spanish and were published in Europe (6), Asia (5), North America (1), and Latin America (2). Sociodemographic variables that showed influence on mortality included male gender, advanced age, frailty of dialysis patients, presence of comorbidities such as cardio-renal syndrome, ischemic heart disease, overweight, obesity, multimorbidity, diabetes, hypertension, a history of stroke, and dementia.

Conclusions:

Severe mortality from SARS-CoV-2 was observed to be higher in patients with chronic kidney disease than in the general population. This was associated with changes in biochemical markers such as elevated troponin, C-reactive protein, liver enzymes, inflammatory markers, decreased lymphocytes, and serum albumin. Additionally, complications associated with mortality included acute respiratory distress syndrome, disseminated intravascular coagulation, septic shock, hypotension, and pneumonia.

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