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Pediatría Atención Primaria
versão impressa ISSN 1139-7632
Resumo
CEMELI-CANO, Mercedes et al. Clinical features and diagnostic difficulties from a prospective study of community-acquired pneumonia in children. Rev Pediatr Aten Primaria [online]. 2021, vol.23, n.91, pp.273-283. Epub 06-Fev-2023. ISSN 1139-7632.
Introduction:
pneumonia is one of the main causes of morbidity and mortality in children. Its management at the paediatric primary care level is not yet solidly established.
Material and methods:
we conducted a prospective study in children aged 1 month to 14 years included in the paediatric caseloads of 9 paediatric primary care centres. The aetiological diagnosis was made by means of serology tests and viral testing in nasopharyngeal aspirate samples. We analysed the association of different variables with the aetiology of pneumonia (viral, atypical bacterial and typical bacterial).
Results:
the study included 92 patients. The mean age (47.58 months) was significantly higher in cases of atypical pneumonia (74.2 ± 42.2) compared to viral pneumonia (36.1 ± 44.5; p <0.0001) and probable typical pneumonia (32.6 ± 21.1; p <0.0001). The distribution by aetiology was 33.7% (95 CI: 24.9 to 43.8) probable pneumococcal, 30.4% (95 CI: 22.0 to 40.5) atypical and 21.7% (95 CI: 14.5 to 31.2) viral. Atypical pneumonia was relatively frequent in children under 5 years (17.1%). Fever (89.1%) and cough (68.4%) were the most frequent symptoms. The most common radiographic feature was alveolar infiltration (53.8%), with no differences between groups. C-reactive protein levels were significantly higher in viral cases (7.6 ± 9.5) compared to probable pneumococcal cases (4.9 ± 10.1) (DM: -2.7; p = 0.0490) and atypical cases (1.7 ± 1.7) (DM: -5.83; p = 0.0111). Amoxicillin was the most frequently used antibiotic (66.3%), which achieved favourable outcomes in all types of pneumonia. The frequency of hospital admission was higher in patients with viral pneumonia (50%) compared to atypical (7.4%; p = 0.0023) or probable pneumococcal pneumonia (12.90 %; p = 0.0100).
Conclusion:
the epidemiology of community-acquired pneumonia in the paediatric population is changing, especially when it comes to atypical bacterial and viral causative agents. The aetiological diagnosis and optimal antibiotherapy regimen for pneumonia are goals yet to be achieved.
Palavras-chave : Paediatrics; Primary Care; Pneumonia.