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Revista de Osteoporosis y Metabolismo Mineral
versão On-line ISSN 2173-2345versão impressa ISSN 1889-836X
Resumo
PORTAL-NUNEZ, S.; DE LA FUENTE, M.; DIEZ, A. e ESBRIT, P.. Oxidative stress as a possible therapeutic target for osteoporosis associated with aging. Rev Osteoporos Metab Miner [online]. 2016, vol.8, n.4, pp.138-146. ISSN 2173-2345.
Senile or involutional osteoporosis is a major problem in the developed world. Recent studies point to increased oxidative stress associated with aging, whether biological or chronological, as an important factor in its development. In this review paper, we focus on bone tissue disorders related to aging, the source of oxidative stress and negative influence on bone tissue. Finally, we consider the potential oxidative stress therapies currently being developed for this disease.
Palavras-chave : oxidative stress; osteoporosis; aging; fragility.