Resumo

MORENO FERNANDEZ, Román Darío; PEDRAZA, Carmen  e  GALLO, Milagros. Adult hippocampal neurogenesis and cognitive aging. Escritos de Psicología [online]. 2013, vol.6, n.3, pp.14-24. ISSN 1989-3809.  https://dx.doi.org/10.5231/psy.writ.2013.2510.

Aging is a normal developmental process associated with neurobiological changes leading to cognitive alterations with preserved, impaired, and enhanced functions. Evidence from animal and human studies is reviewed to explore the potential role of hippocampal plasticity on age-related cognitive changes with special attention to adult hippocampal neurogenesis. Results from lesion and stimulation strategies, as well as correlation data, support either a direct or modulatory role for adult newborn neurons in cognition at advanced ages. Further research on this topic may help to develop new treatments and to improve the quality of life of older people.

Palavras-chave : Adult Hippocampal Neurogenesis; Aging; Cognitive Decline; Spatial Memory.

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