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Journal of Negative and No Positive Results
versión On-line ISSN 2529-850X
Resumen
GONZALEZ-CASTRO, MI; RAMIREZ-FRAIRE, RO y RIVAS-GARCIA, F. Neurotoxicity of pesticides. Brief update. JONNPR [online]. 2022, vol.7, n.4, pp.376-384. Epub 25-Sep-2023. ISSN 2529-850X. https://dx.doi.org/10.19230/jonnpr.4824.
Introduction:
Pesticides are necessary for the development of today's society, although they pose a risk to public health, the ecosystem, human health, people directly and indirectly exposed through the food chain and/or the environment. In fact, more and more studies show neurotoxicity derived from acute and/or chronic poisoning due to exposure to pesticides.
Method:
A brief bibliographical review on the toxicity of these chemical products was carried out, in relation to the damage they can cause in the nervous system. Scientific articles published in English and Spanish were examined, by searching databases such as: Scielo, Medline, Springer, Scopus and Science Direct, of articles that were disclosed during the period between 2017 and 2022, according to the criteria established by the PRISMA statement.
Results:
Pesticides are one of the most widely used environmental contaminants, which can generate numerous benefits for agriculture; however, they are increasingly related to neurotoxicity derived from chronic exposure, which occurs with the development of chronic neurodegenerative diseases.
Conclusions:
More studies are needed to address neurotoxicity induced by exposure to pesticides, as well as the need to strengthen all systems of prevention, control, and measures that guarantee the health of the exposed population.
Palabras clave : Pesticides; neurotoxicity; Alzheimer's; Parkinson; oxidative stress.