SciELO - Scientific Electronic Library Online

vol.59 número3Dieta y cáncer de vejigaObstrucción primaria del cuello vesical en el varón índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google


Archivos Españoles de Urología (Ed. impresa)

versión impresa ISSN 0004-0614


LUJAN GALAN, Marcos et al. Impact of the weather on the serum levels of prostatic specific antigen (SPA). Arch. Esp. Urol. [online]. 2006, vol.59, n.3, pp.247-252. ISSN 0004-0614.

Objetives: To analyze the impact of season and weather parameters on serum PSA values in men without prostate cancer. Methods: Retrospective study including medical records from the Spanish arm of the European Randomized Study of Screening for Prostate Cancer (ERSPC). Exclusion criteria: prostate cancer diagnosis, PSA = 10 ng/ml, or PSA = 3 ng/ml and/or digital rectal examination abnormalities unless a negative prostate biopsy was provided. Univariate relationships between PSA value, season and several weather parameters were assessed. A multivariate logistic regression model was used to identify independent predictors of a PSA value =3 ng/ml. Results: A total of 2,147 men entered into the study. Median age and PSA level were 57 years and 0.9 ng/ml respectively. A non-significant trend to higher PSA levels was observed during autumn and winter. Multivariate logistic regression analysis identified only maximum temperature (p<0.001), minimum temperature (p=0.001) and age (p<0.001) as independent predictors of a PSA value = 3 ng/ml. Mean age-adjusted PSA levels at maximum temperatures of <=15ºC, 16-20ºC, 21-25ºC and =26ºC were 1.25, 1.20, 1.17 and 1.09 ng/ml respectively. Conclusions: PSA levels are slightly higher during cold weather conditions. Because of the small magnitude of this PSA increment we do not recommend to change biopsy indication based solely on climatic parameters.

Palabras clave : Prostate-specific antigen; Prostate cancer; Weather climate.

        · resumen en Español     · texto en Español     · Español ( pdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons