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Archivos Españoles de Urología (Ed. impresa)

versión impresa ISSN 0004-0614


PIANA, Mauro et al. Penile leiomyosarcoma: Case report and bibliographic review. Arch. Esp. Urol. [online]. 2006, vol.59, n.7, pp.728-731. ISSN 0004-0614.

Objective: Primary penile leiomyosarcoma is a rare entity. Since 1930 only 30 cases have been reported in the bibliography. We wanted to add a new case to the international literature, in addition to a review of all available publications on the topic from 1957. A 54-year-old patient presented with a lobulated 8x4x3 cm lesion in the balanopreputial groove over two years; he was treated initially with partial penectomy and subsequently with total penectomy. We analyze the evolution, progression and adjuvant treatments of this rare pathology. Methods/Results: We report one case with its clinical presentation, diagnostic tests performed for staging, treatment and follow-up. Conclusions: The first case of penile leiomyosarcoma was described by Levi in 1930. In 1957 Ashley and Edwards reported the first case in the British literature and in 1963 Pack reported the first in the American literature. MacKenzie et al. were the first to recognize two types of leiomyosarcoma: superficial and deep. The first develop from smooth muscle cells from the superficial dermal layers of the glans penis or distal third of the penis, they are generally asymptomatic and less malignant, rarely invading deeper structures and without involvement of the urethra on physical exam. The best prognostic predictors are type of tumor at presentation (superficial vs. deep) and treatment choice, being total penectomy more effective for failures of local resections than for primary treatment of deep tumors.

Palabras clave : Penile leiomyosarcoma.

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