Abstract

ARRATIA-MAQUEO, Jorge A.; CORTES-GONZALEZ, Jeff R.; GARZA-CORTES, Roberto  and  GOMEZ-GUERRA, Lauro S.. Prospective study of prostate cancer's detection rate at our hospital in Northeast Mexican patients with PSA values between 2.6 y 4 ng/ml. Arch. Esp. Urol. [online]. 2010, vol.63, n.4, pp.287-290. ISSN 0004-0614.

Objectives: To find the detection rate of prostate cancer (PCa) in our population with PSA values between 2.6 and 4 ng/ml. Methods: We included 33 consecutive patients with a median age of 66 years, that had a Transrectal Ultrasound (TRUS) guided biopsy with PSA between 2.6-4 ng/ml. Patients were divided into 2 groups. Group 1: patients with normal Digital Rectal Examination (DRE) and Group 2: Patients with DRE with asymmetry not definitive of PCa. Exclusion criteria: known history of PCa, intraepithelial neoplasia or Positive DRE. Statistical analysis: Chi square, t-student and Fischer exact test. Results: Twenty eight percent of the patients (9) had positive biopsy for PCa. Fifty six percent (5) were Gleason 6 and 44% (4) Gleason 7 (3+4). Group 1 had 59% (20) and Group 2 41% in. In Group 1 16% (3) had positive biopsy for PCa vs 46% (6) in group 2 (p 0.04) RR 3.07. Conclusions: There are traces that the detection rate in our population could be lower in comparison with what has been reported in the literature. DRE is crucial in the initial evaluation; asymmetry could increase 3 fold the risk of having PCa.

Keywords : Prostatic cancer; PSA; Biopsy.

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