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Actas Urológicas Españolas

Print version ISSN 0210-4806


TRABA VILLAMEYTIDE, M.L.; ORTS COSTA, J.A.  and  MORELL, M.. Study of a intestinal enteroliths in human patient with colon adenocarcinome: Is it similar to renal calculi?. Actas Urol Esp [online]. 2006, vol.30, n.2, pp.206-214. ISSN 0210-4806.

This work shows the study performance to intestinal enterolithis from a 91 year old patient with multiple enterolithiasis confirmed by abdominal X-ray and TAC analyses showing the presence of intestinal, renal and bile stones. This enterolithis is associated with colon adenocarcinoma. The enteroliths were obtained by hemicolectomia and were analyzed by infrared spectroscopy (IR), giving nonstoichiometry carbonate apatite whitloquite-like with, possibly, organic material. By atomic emission spectroscopy we found Ca, Mg, K, Na y K (mg/100 mg of calculi) and Zn, Ba, Mn, Fe, Cu, Si, Ti and Br in minor proportion (µg/100 mg of calculi). Because of calculi morphology and the IR spectra (non-stoichiometry carbonate apatite) we carried out analysis by high performance liquid chromatography (HPLC) and found coproporphyrin (about µg/g of calculi) and uroporphyrin, protoporphyrin and heptacarboxy-porphyrin in minor extent. Calculi were also studied by scanning electronic microscopy and EDX and X-ray diffraction giving crystals of CaP4O11. All these results show that intestinal enteroliths composition are similar to renal calculi although its morphology differs from renal calculi.

Keywords : Enterolithiasis; Carbonate apatite whitloquite-like; Coproporphyrin; Calcium phosphate (CaP4O11).

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