Abstract

MARTI MESTRE, Joaquín et al. Nested variant of urothelial carcinoma: A rare histological variant. Actas Urol Esp [online]. 2009, vol.33, n.1, pp.90-92. ISSN 0210-4806.

The nested variant of urothelial carcinoma is a rare histological tumor of urinary bladder. The clinical symptoms are similar to those of the classic urothelial carcinomas. Its macroscopic appearance can be very subtle due to its preference for a submucosal growth leading to a possible delay in diagnosis. Microscopically, it is characterized by nests and tubules formation. While the neoplastic cells exhibit low-grade histological features, the growth pattern is widely infiltrative conferring this neoplasia a bad prognosis even if a radical treatment is performed. We present a case of a patient affected by a nested variant of urothelial carcinoma of urinary bladder to whom a radical cystoprostatectomy was performed and adjuvant chemotherapy was given. He is alive and free of disease one year after the diagnosis.

Keywords : Bladder carcinoma; Urothelial carcinoma; Nested variant.

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