Abstract

HERNANDEZ SIERRA, B. et al. Clinical, epidemiological and taxonomic aspects of systemic candidiasis in an intensive care unit. Med. Intensiva [online]. 2009, vol.33, n.3, pp.144-147. ISSN 0210-5691.

The clinical and epidemiological profile and survival of patients admitted into our intensive care unit (ICU) was analyzed. A retrospective-prospective case series from 2002 to 2004 and 2005 to 2006, respectively, of patients diagnosed with systemic candidiasis in an ICU in a tertiary hospital was studied. Twenty-six cases with systemic candidiasis were included (75% of the cases were male). These subjects underwent multiple vascular or drainage interventions and had a prolonged length of stay in ICU. The first motive to enter ICU was sepsis. Candida albicans (CA) was isolated in 53.8% of cases versus 46.2% for other Candidae (CNA). Over the last years, we have observed a progressively higher incidence for CNA (p = 0.02). We registered an especially high mortality rate (42%), that is higher in the CA group. «Sevilla Score» defined the mortality in the progressive risk groups (p = 0.026).

Keywords : Candidiasis; Candida; Candida albicans; Fungemia; Intensive care units; Fluconazole.

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