Abstract

MATA RUIZ, lván de la  and  ORTIZ LOBO, Alberto. Biases and troubles on new antipsychotics investigation. Rev. Asoc. Esp. Neuropsiq. [online]. 2001, n.79, pp.57-74. ISSN 2340-2733.

We describe the limitations of randomised clinical trials of drugs because of pifalls in methodological design, analysis and interpretation of results, ethical conflicts and publication bias. We analyse trials on new antipsychotics as example of these pitfalls and limitations.

Keywords : Pharmacological investigation; Randomised clinical trial; Publication bias; Ethics; New antipsychotics; Atypical antipsychotic.

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