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Revista de la Asociación Española de Neuropsiquiatría

On-line version ISSN 2340-2733Print version ISSN 0211-5735


VERDURA VIZCAINO, Ernesto José; BALLESTEROS SANZ, Daniel  and  SANZ-FUENTENEBRO, Javier. Atypical antipsychotics plasma level monitoring. Rev. Asoc. Esp. Neuropsiq. [online]. 2012, vol.32, n.115, pp.499-519. ISSN 2340-2733.

Introduction: Analysis of psychotropic drug concentration in blood or serum is a mean to ascertain the pharmacokinetic profile of the treated subject. This is known as drug monitoring. Currently plasma antidepressants, antipsychotics, mood stabilizers, drugs substitutes for opioids, anxiolytics and hypnotics can be monitorized. Methodology: We reviewed all published articles on monitoring of psychotropic drugs in general from 1975 to 2010. As a source of information used: Embase, Medline and Pubmed. Objetive: To review the current state of science in relation to the monitoring of atypical antipsychotics. Antipsychotic plasma level monitoring is crucial both to assess adherence and to determine the plasma drug concentration. Conclusions: The monitoring of antipsychotics and other psychotropic drugs, is an established practice must be known and be maintained by a psychiatrist, like other aspects of psychopharmacology, for a therapeutic exercise based on the current state of science.

Keywords : Concentration; Monitorization; Psychotropic Drug; Antipsychotic.

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