Abstract

ORTIZ LIBRERO, M. et al. The importance of comorbidity in acute renal failure evaluated by nephrologist. Nefrología (Madr.) [online]. 2009, vol.29, n.5, pp.430-438. ISSN 1989-2284.

Aims: To study the features of acute renal failure (ARF) in our hospital and to determine prognosis and mortality associated factors. Methods: This is a retrospective study analyzing the ARF episodes observed in our center during a two years period (2005-2007). ARF was considered when a sudden rise in serum creatinine concentration was more than 0, 5 mg/dl in patients with normal renal function and more than 1 mg/dl in patients with previous mild to moderate chronic renal failure. We analyzed epidemiologic, clinical, laboratories results, therapeutics and prognosis factors. Results: Two hundred and one patients were evaluated (62, 7% males; Age= 67,35 ± 16,38 years (63,68% >65 años); Comorbility Index of Charlson was 3,49 ± 2,43). 115 ARF episodes occurred in patients with previous renal failure. ARF was pre-renal in 52,7%, renal in 34,8% and post-renal in 8,5%. 35,8% of ARF patients had oliguria or anuria. The mean duration of ARF/hospitalization was 22,47 days (22,47 ± 21,83). The percentage of resolved ARF was 70, 1%. Mortality was 30,8%. The univariate analysis showed that comorbility Index of Charlson, oliguria, low serum albumin, low cholesterol and anemia were significantly associated with mortality (p < 0,05). However, only Charlson Index, oliguria and low serum cholesterol were independent predictors of mortality in multivariate analysis. Mortality predictive model was carried out. Conclusion: Highest basal comorbility of patients, oliguria and malnutrition inflamation dates are independent predictors of mortality in patients with acute renal failure.

Keywords : Acute renal failure; Comorbidity; Oliguria; Malnutrition-Inflamation Syndrom.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )